The Eppley Structural Biology Facility is equipped with the latest industry standard equipment to create large amounts of extremely pure protein for a variety of uses as well as the equipment to collect and solve atomic resolution structures using X-ray Crystallography or NMR.
The Structural Biology Facility is divided into four main laboratory components (Detailed information is available by clicking on any of the Labs shown in the above image) :
Protein Expression and Purification (PrEP) Lab – This lab is dedicated to the high yield production, purification and labeling of protein.
Crystal Screening and Growth (CSG) Lab – This lab uses the Formulatrix industry-standard automated crystallization platform to set up, image and electronically evaluate experiments.
X-ray Crystallography Lab – This lab has a Rigaku protein crystallography instrument composed of an FRE rotating anode generator and dual R-Axis IV++ detectors configured for the collection of high resolution X-ray diffraction data.
Nuclear Magnetic Resonance (NMR) Lab – This lab has three NMR spectrometers (400, 500 and 600 Mhz) allowing the lab to perform a wide variety of NMR data collection including protein structural data up to 30 kDa.