Crystal Screening and Growth (CSG)

CSG with key equipment labeled

The CSG occupies about 500 sq. ft. of the Scott Research Tower and uses robotics to automatically screen and refine crystallization conditions while maintaining detailed electronic experimental records using the Formulatrix RockMaker LIMS system.

IdDescriptionImage
aRockMaker Database Server
bFreedom EVO 150 is controlled by RockMaker to create random and grid screens directly in the experiment plate or deep well screens. The Freedom EVO 150 is used to mix the well solutions only. Crystallization drops are finished with the Phoenix or by hand in the case of 24 well hanging drops.
cThe Formulatrix RockImager 182 is used to automatically image 96 and 24 well crystallization experiments. It holds 182 plates at a time. It can image experiments with both visible and UV light.
dThe Crystal Gryphon is a small, fast and affordable option for setting up all of your crystal plates. The Crystal Gryphon fits into tight lab spaces and tight lab budgets.

The 96-channel positive displacement head quickly fills screen reservoirs and protein wells. The head has no disposable tips, so the cost of operation and environmental waste is minimized.

The 1-channel non-contact dispenser quickly aspirates and dispenses your proteins allowing your plate to be sealed without evaporation being a problem. This dispense head is designed specifically to handle proteins, features flow-through washing and positive displacement aspiration, to handle all of your proteins.
fRuMed 3000 series incubators with programmable temperature profiles. Each incubator can hold around 1000 experiment plates. Typically they are set to maintain constant temperature at 20°C. A dedicated cold room is also available for crystallization at 4°C.