Nuclear magnetic resonance spectroscopy is a powerful tool for basic research that improves our knowledge at the molecular level. It also plays an important role in drug discovery by verifying the structure of small molecule inhibitors.
These machines provide essential support to various grants of investigators and enable excellent training to students with an interest in nuclear magnetic resonance. Off-campus users also are encouraged to use our facility. The facility is supported by a CORE grant from the National Cancer Institutes, as well as the Nebraska Research Initiative. Facility operational costs are partially covered via minimal charge-backs to the users.
Spectrometers
| Equipment | Description |
|---|---|
| Bruker Avance III 400 MHz NMR Spectrometer | The Bruker Avance III 400 MHz NMR Spectrometer is equipped with a multi-nuclear observe broad band 5mm NMR probe for liquid state samples. The spectrometer is also equipped with an automated 24 position “SampleCase” robotic sample changer for unattended data acquisition and improved sample throughput. |
| Bruker Avance III HD 600 MHz | The Bruker Avance-III HD 600 MHz instrument is dedicated to the studies of small proteins and their interactions with a variety of ligands, including lipids, drugs, DNA, sugar, and partner proteins. equipped with a multi-nuclear observe broad band 5mm NMR probe for liquid state samples. The spectrometer is equipped with an automated 24 position “SampleCase” robotic sample changer for unattended data acquisition and improved sample throughput. |